Senior Manager, Clinical Genomics Laboratory Services

Build Our Future Together

Reporting to the Clinical Laboratory Director, the Senior Manager, Clinical Laboratory Services oversees and manages the daily operations of the Regeneron Clinical Genomics Laboratory, ensuring compliance with all regulatory requirements. The role combines hands-on, end-to-end oversight of complex laboratory tests and procedures with stakeholder collaboration, data analysis, participation in test validation, and the writing and maintenance of laboratory documentation in accordance with regulatory standards. The Senior Manager also serves as the scientific lead for variant classification decisions and leads quality and continuous improvement efforts, including implementing changes to mitigate risks. The role includes leading, training, and mentoring team members in clinical laboratory procedures. This position requires comprehensive knowledge of clinical quality requirements, including CLIA, NY CLEP, and CAP, and NYSED-issued credentials as a Clinical Laboratory Technologist or Technical Director.

When & where:

• Work Location: Tarrytown, NY
• Work model/flexibility: 4 days per week on site

Discover your role:

• Direct and oversee daily NextGen Sequencing clinical laboratory operations, including workflow, sample processing, testing, and post-analytical processes, to ensure efficient and accurate functioning.

• Provide operational leadership and technical guidance, present organizational capabilities, define the scope of work, and drive execution to deliver results in a fast-paced environment.

• Ensure operational adherence to all regulatory standards and maintain compliance with New York State Department of Health regulations, CLIA and CAP guidelines, and requirements of other relevant accrediting agencies by monitoring and reviewing laboratory processes and procedures. Implement and monitor quality control procedures to guarantee accurate and reliable test results.

• Participate in design and performance of test validation processes, including method validation, performance evaluation, and verification of assays.

• This role may serve as Variant Scientist, supporting technical analysis, curation, and classification of all genetic variants identified in patient samples. This requires the use of laboratory platforms for variant prioritization and automated ACMG classification scoring.

• Assist in the development and maintenance of required documentation, including work instructions/SOPs, policies, and protocols.

• Promote a continuous improvement mindset and identify opportunities for process enhancements and risk mitigation.

• Analyze and report quality indicators, tracking trends, and communicating critical compliance and quality risks.

• Provide people leadership to laboratory staff, including hiring, training, mentoring, performance management, and day-to-day supervision, fostering a culture of accountability and professional growth.

This role requires:

• A doctoral degree in a chemical, physical, biological, or clinical laboratory science (or medicine) from an accredited institution.
• Valid full New York State Technologist License or Technical Director in Genetic Testing
• 5 + years of experience working in a next generation sequencing clinical laboratory. Strongly preferred: Variant curation and data analyst experience.
• 2+ years of appropriate laboratory training/experience in the specialty
• Project management certificate is a plus

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

 

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$137,100.00 - $223,500.00