Senior Research Associate

Department Overview

This position is part of a research team investigating how Mycobacterium tuberculosis (Mtb) drives granuloma formation in the lung, primarily through imaging lung tissues using Mtb-specific nanobodies. The successful candidate will independently design and conduct experiments, develop and troubleshoot protocols, and analyze data. Research activities will involve lung tissue cryosectioning and immunostaining, histology, multiplex imaging, fluorescence microscopy, protein purification, PCR, plasmid preparation, cell culture, transfection, and Western blotting. The successful candidate will also oversee laboratory operations, including ordering supplies, maintaining laboratory infrastructure, and ensuring compliance with safety regulations. They will train new laboratory personnel and supervise junior lab members in experimental procedures and techniques. Additional responsibilities include participating in weekly lab meetings and contributing to the preparation of research manuscripts, reports, and grant applications.

Function/Duties of Position

• Lead project management in key areas of research. Independently design and conduct experiments. Develop standard operating procedures and new methods and protocols.

• Work with PI to develop research goals and strategic plan for achieving them.

• Analyze and interpret data, make figures for manuscripts, grants, and presentations.

• Manage lab infrastructure including managing inventory and ordering supplies.

Required Qualifications

• PhD in relevant field AND 1 year of relevant experience OR

• Master's Degree in relevant field AND 5 years of relevant experience OR

• Bachelor's Degree in relevant field AND 9 years of relevant experience

• Histology, microscopy, excellent communication skills including strong writing ability, strong organizational ability

• Protein purification, protein conjugation

• Ability to perform the job duties with or without accommodation.

Preferred Qualifications

• Cell culture, immunohistochemistry
• Presentation skills (poster, short talk)

Additional Details

Occasional evening and weekend work. Work with human tissue and blood samples.

Why apply to OHSU?

We are Oregon's only public academic health center. In addition to caring for patients, we lead groundbreaking research. We also train the next generation of health care professionals. As Portland's largest employer, we give you opportunities to learn and advance in a system of hospitals and clinics across Oregon and Southwest Washington. All are welcome. OHSU welcomes people of all ages, ethnicities, genders, national origins, religions and sexual orientations. We are striving to build an anti-racist, multicultural institution and encourage people with diverse backgrounds to apply. To request reasonable accommodation, contact askhr@ohsu.edu